Dihydrostreptomycin sulphate CAS NO.5490-27-7

Name: Dihydrostreptomycin sulphate
SKU: 5490-27-7
Availability: InStock

Dihydrostreptomycin sulphate for veterinary use is

bis[N,N′-bis(aminoiminomethyl)-4-O-[5-deoxy-2-O-[2-deoxy-2-

(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl)-α-

L-lyxofuranosyl]-D-streptamine] tris(sulphate), the sulphate

of a substance obtained by catalytic hydrogenation of

streptomycin or by any other means. Stabilisers may be

added. The potency is not less than 730 IU/mg, calculated

with reference to the dried substance.

IDENTIFICATION

A. Examine by thin-layer chromatography (2.2.27) using

a plate coated with a 0.75 mm layer of the following

mixture: mix 0.3 g of carbomer R with 240 ml of water R

and allow to stand, with moderate shaking, for 1 h ; adjust

to pH 7 by the gradual addition, with continuous shaking,

of dilute sodium hydroxide solution R and add 30 g of

silica gel H R.

Heat the plate at 110 °C for 1 h, allow to cool and use

immediately.

Test solution. Dissolve 10 mg of the substance to be

examined in water R and dilute to 10 ml with the same

solvent.

Reference solution (a). Dissolve 10 mg of

dihydrostreptomycin sulphate CRS in water R and dilute

to 10 ml with the same solvent.